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By week 16, a larger proportion of AXA1125-treated subjects (3540%) than those in the placebo group (825%) reached clinically relevant thresholds for MRI-PDFF reductions of 30%, ALT reductions of 17 IU/L, and cT1 reductions of 80 ms

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Variants, such as the highly common C677T or A1298C mutations reduce the activity of the MTHFR enzyme, meaning your body produces less functional L-methylfolate

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